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Todd Lee M.D. on Instagram: "Alpha = feminizing. ERalpha binding is what gives the soft, bloated, puffy look. Masteron inhibits ERalpha. Most likely through an allosteric change to the binding domain so it cannot accept an E2 molecule. This is not competitive inhibition where something sits in the active site with higher affinity. It is altering the site so E2 can’t bind in the first place. Beta = health and anabolism. Masteron does not inhibit ERbeta. Primo = destroys E2. When E2 is gone nothin
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