RFdiffusion is an open source method for structure generation, with or without conditional information (a motif, target etc). It can perform a whole range of protein design challenges as we have outlined in …

Jul 11, 2023 · In a manner analogous to networks that produce images from user-specified inputs, RFdiffusion enables the design of diverse functional proteins from simple molecular specifications.

Dec 3, 2025 · Today we are releasing RFdiffusion3 as open-source software. This state-of-the-art AI model for biodesign is capable of generating new proteins that interact with any type of molecule …

Jul 11, 2023 · We have developed a guided diffusion model for generating new proteins called RFdiffusion. With prior design methods, tens of thousands of molecules may have to be tested …

Introduced in Atom level enzyme active site scaffolding using RFdiffusion2, RFdiffusion2 expands on the enzyme scaffolding capabilities of diffusion-based protein design by giving researchers finer …

Jul 20, 2025 · Explore RFdiffusion, a generative AI that moves beyond predicting protein structures to actively designing new ones for specific scientific applications.

Jul 16, 2025 · We’re excited to share that the beta version of the official RFdiffusion documentation is now live! This resource is designed to support users at all levels – from those new to RFdiffusion to …

Jul 25, 2025 · RFdiffusion represents a versatile and powerful protein design platform based on diffusion models. Its modular architecture supports diverse design tasks while providing extensive …

Apr 10, 2025 · Our latest deep-learning model, RFdiffusion2, can be used to generate enzyme backbones with custom active sites from simple descriptions of chemical reactions. This removes …

Rosetta Fold (RF) dissusion is an open source method for structure generation, with or without conditional information (a motif, target etc). It can perform motif scaffolding, unconditional protein …