A persistent fever without an apparent infection can be a sign of kidney cancer. This type of fever occurs as the body's ...

Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, ...

Many systemic diseases have unique oral manifestations that can aid a primary-care clinician in making a diagnosis. Careful oral examination may reveal findings suggestive of a systemic disorder.

The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial. Ann Intern Med 2005;142:953-962.

What is lupus, and what does it do to your body? I just had a friend diagnosed with it after many months of tests. — T.S.B.

IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care Res (Hoboken) 2010;62:316-322. Crossref. PubMed.

Patients with systemic autoimmune rheumatic diseases who contract COVID-19 may have a higher risk for end-organ failure than those without such diseases, according to a speaker at ACR Convergence ...