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DCx sees potential to build multifunctional ADCs using the same technology Repare used to create its small molecule synthetic lethal therapies.
The biotech has nominated MB-111, a drug it's developing as a treatment for elevated triglycerides, as its first clinical development candidate.
The firm is studying the combination in the first-line setting for head and neck cancer patients who had a PD-L1 combined positive score of less than 1.
Researchers at AACR discussed what's next for the drug class, given the disappointing activity of tiragolumab with Tecentriq ...
The company said it took financial hits from the Inflation Reduction Act's Medicare Part D redesign, which included higher ...
DCx will gain rights to technology, targets, and preclinical programs from Repare along with lab space and staff in Montreal.
The firm enrolled the first patient at Florida's BayCare Morton Plant Hospital, and the study procedure went according to protocol, per an investigator.
The nonprofit says its pipeline offers more affordable and accessible therapeutics, including point-of-care CAR-T cell therapy for leukemia and lymphoma.
The clinical trial will include nearly 150 patients with advanced hepatocellular carcinoma that expresses glypican-3.
In a Phase I study presented at AACR's annual meeting, 71 percent of patients who hadn't received a prior anti-HER2 ADC responded to the drug.
The firm is expecting Phase III readouts this year for its FGFR2b drug bemarituzumab and is advancing a second KRAS inhibitor to the clinic.