Background The aetiology and pathogenesis of IBD are intricate, involving genetic and environmental factors. Notably, cigarette smoking has contrasting effects, being detrimental to Crohn’s disease ...

Colorectal cancer (CRC) represents a major global health issue, ranking as the third most common tumour and the second leading cause of cancer-related mortality worldwide.1 Distant metastasis is the ...

Background Limited evidence supports colonoscopy surveillance practices among individuals aged <50 years. Objective To compare the risk of polyp recurrence and colorectal cancer (CRC) among young and ...

Objectives To investigate the occurrence of postinfectious IBS in routine outpatient care, comparing different types of GI infection and its interaction with psychosomatic comorbidity. Design ...

This article has a correction. Please see: Correction:Real-life multicentre study of lumen-apposing metal stent for EUS-guided drainage of pancreatic fluid collections - October 01, 2022 ...

BACKGROUND There is a paucity of data in the literature on the risks associated with, and optimal management of, pregnancy in patients with autoimmune hepatitis (AIH).

Objective Serrated lesions such as sessile serrated adenomas or polyps (SSA/Ps) are important colorectal cancer precursors, but aetiological factors for these lesions are largely unknown. We aimed to ...

Objective In human chronic liver disease, there is association between ductular reaction (DR) and fibrosis; yet, the mechanism triggering its onset and its role in scar formation remains unknown.

Of 52 patients receiving a mean dose of 2.5g sulphasalazine/day as maintenance therapy for ulcerative colitis, 35 were found to have one or more drug-induced red cell abnormalities, which were not ...

Non-erosive reflux disease (NERD) is defined as the presence of classic symptoms of gastro-oesophageal reflux disease (GORD) in the absence of oesophageal mucosal injury (or Barrett’s oesophagus) as ...

Objective The definition of acute-on-chronic liver failure (ACLF) based on cirrhosis, irrespective of aetiology, remains controversial. This study aimed to clarify the clinicopathological ...

BACKGROUND/AIM: Nitric oxide (NO) may be involved in non-adrenergic non-cholinergic (NANC) inhibitory innervation of the sphincter of Oddi (SO). The effects of topical application of glyceryl ...