A distinct inflammatory profile marked by neutrophil activity and cytokine elevation may underline poor biological response ...

Biologics, including medications like mepolizumab and dupilumab, are widely prescribed for patients with severe asthma and ...

The FDA recently approved mepolizumab for treating adults with inadequately controlled COPD and an eosinophilic phenotype, ...

Expert Rev Resp Med. 2008;2(5):617-629. The studies of mepolizumab have shown that this treatment was safe and well-tolerated; in fact, in the 3-month studies there were more withdrawals due to ...

Novel Anti-inflammatory Drugs The clinical development programmes for novel drugs designed to manipulate the immune system in asthma need to ensure the safety of the volunteers against acute- or ...

Patients with eosinophilic granulomatosis with polyangiitis experienced significant improvements in a variety of outcomes with mepolizumab at 12 months, according to a study published in Annals of ...