Bregman singled off the left field wall with two down in the fifth inning Friday. As he made the turn at first, he slowed down as the ball was fielded and thrown back into the infield. As Bregman arrived back at first, he immediately signaled to the dugout that he needed to come out of the game.

Red Sox third baseman Alex Bregman could be nearing a trip to the injured list after leaving Friday’s game with right quadriceps tightness, manager Alex Cora said.

Red Sox third baseman Alex Bregman walks off of the field with a trainer after hitting a single against the Baltimore Orioles during the fifth at Fenway Park on May 23, 2025 in Boston, Massachusetts. (Photo by Brian Fluharty/Getty Images) Getty Images