Dynamin is a protein that plays a central role in endocytosis—the process where cells internalize substances by wrapping them in cell membrane vesicles. For a vesicle to detach, the neck of the ...
For numerous fundamental processes of life, the formation of certain protein patterns is essential. Protein pattern formation ...
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AI turns routine pathology slides into powerful maps of the tumor immune landscape
A large study shows that routine H&E pathology slides contain rich spatial proteomic signals that can be decoded by AI to ...
African Swine Fever Virus, ASFV, Viral Entry, Host Cell Invasion, CD163, Siglec-1, Macropinocytosis, Endosomal Escape, Immune Evasion, Signaling Pathways Share and Cite: Marcelino, K.B. and Fang, G.J.
Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation
This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...
Cross-species functional genomics identify ribosomal protein genes as key regulators of cardiomyocyte proliferation and heart development, implicating them as candidate modifiers for HLHS and ...
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AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer
An artificial intelligence (AI) model created by integrating clinical, molecular, and histopathological data significantly ...
Microsoft and Providence Health have released GigaTIME, an open-source AI that generates virtual tumor microenvironment data ...
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