Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists have now shown in mice: mast cells function as a sensor that signals the animals to avoid antigens, ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the immune system that spring into action with histamine-filled granules in response ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

In a recent study published in Nature, researchers used a mouse model to show that mast cells and immunoglobulin E (IgE) are the key orchestrators of antigen-specific avoidance, a behavioral ...

Mastocytosis is a rare condition where an excessive amount of mast cells gather in the organs and tissues of the body. It can affect the skin, lymph nodes, bone marrow, and other organ systems. Mast ...

Although many topical or systemic antibiotics exist to treat acne vulgaris, the common inflammatory skin disease is not fully treatable. A new article published in The Journal of Clinical and ...