Mitochondria produce most of the cellular ATP by the process of oxidative phosphorylation (OXPHOS) and generate most of the endogenous oxygen radicals as a toxic by-product. In addition, mitochondria ...
Here we present a method for the fabrication of microarrays in which presynthesized oligonucleotides are ejected onto a glass surface by a Bubble Jet printing device. The oligonucleotides are then ...
BUFFALO, N.Y. -- A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in ...
The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...
Two of the critical issues that arise when examining DNA microarray data are (1) determination of which genes best discriminate among the different types of tissue, and (2) characterization of ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 33 (Aug. 15, 2006), pp. 12311-12316 (6 pages) We have developed methods for using DNA array technology to ...
In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...
Determining true HER2 status in breast cancers with polysomy using alternative chromosome 17 reference genes: Implications for trastuzumab therapy. Background: Systemic chemo- and chemoradiation ...
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