This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Activating Transcription Factor 5 (ATF5) is a member of the ATF/CREB family of transcription factors and plays a pivotal role in managing cell stress responses, differentiation and survival. Its ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

Demonstrating their technique in mouse embryonic stem cells, the researchers found that they could calculate approximately when a particular region starts to be transcribed, based on the length of the ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular ...

The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across more than 400 tissue and cell types. Chromatin immunoprecipitation ...

Humans have it. So does Drosophila. But not yeast. That "it" is a small pause at the start of gene activity—a brief molecular ...

In a recent preclinical study published in the Journal of Clinical Investigation, researchers in the United States of America investigated the role of the transcription factor KLF15 (short for Kruppel ...

Researchers at University of Tsukuba have comprehensively analyzed genomic binding data of transcription factors (proteins that regulate gene expression) in humans, revealing a substantial amount of ...