The immune system provides an integral defense against cancer growth and progression. Activating an anti-tumor immune response relies on several biological steps that can ultimately result in the ...

The researchers say that, to their knowledge, this is the first demonstration of programmable, site-specific integration of a ...

Cancer immunotherapy has completely changed our understanding of how cancer can and should be treated. A prime example is chimeric antigen receptor (CAR) T-cell therapy, where T cells are harvested ...

Cause-Specific Mortality in a Cohort of 1,435 Patients With Hodgkin Lymphoma Treated Between 1985 and 2014: A Nationwide Chilean Cohort Study Healthy volunteers were recruited and underwent ...

Immune checkpoint inhibitors have reshaped cancer treatment over the past decade, but the same immune activation that shrinks tumors can also turn against healthy tissue, including the brain. A ...

Preclinical research has shown that CAR T cells directed against the urokinase plasminogen activator receptor can attack both ...