AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...

X chromosome dosage compensation does occur in germ cells. A study published today in the open access journal Journal of Biology reveals that expression of the genes on the X chromosome is doubled in ...

Geneticists uncover new insights into how sex chromosome systems work in the platypus and the chicken -- which will lead to better understandings of our own sex chromosome evolution and gene ...

Philosophical Transactions: Biological Sciences, Vol. 376, No. 1833, Theme issue: Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates ...

Human females have two X chromosomes, and males only one. This chromosome imbalance also extends to other branches of the animal kingdom. Interestingly, the humble fruit fly has devised a different ...

X chromosome inactivation is an epigenetic dosage compensation mechanism in female mammals driven by the long noncoding RNA, Xist. Although recent genomic and proteomic approaches have provided a more ...

Gene dosage mechanisms are required to maintain the expression of haploinsufficient genes properly, which, if misregulated, can lead to many developmental disorders. For the first time, researchers ...

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell.