Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of CRISPR-Cas9 for gene knockout has given researchers a powerful ...

CRISPR technology has revolutionized biology, largely because of its simplicity compared to previous gene editing techniques. However, it still takes weeks to learn, design, perform, and analyze ...

CRISPR/Cas9 gene-editing technology combined with next-generation sequencing has opened the door for genome-wide screens to identify novel protein functions. CRISPR/Cas9 screens require the delivery ...

The practice of genetic modification is as old as humanity. For thousands of years, humans have bred crops, livestock and even pets that possess desirable traits. This selective process, which alters ...

Scientists have fine-tuned their delivery system to deliver a DNA editing tool to alter DNA sequences and modify gene function. The improved 'hit and run' system works faster and is more efficient.

The last 10 years have witnessed the remarkable advancement of CRISPR-Cas9 technology from discovery to early development to its clinical application to treat various diseases. However, CRISPR-Cas9 ...

Over the last decade, RNAi-based loss-of-function screens have proven to be an effective tool to identify essential genes and critical genetic drivers for a host of responses as well as potential drug ...

WALTHAM, Mass.--(BUSINESS WIRE)--Horizon Discovery, a PerkinElmer, Inc. (NYSE:PKI) company, today announced that its gene editing and modulation portfolio is expanding to include a new family of ...

Penn and CHOP researchers will utilize the new protocol to distribute customizable drugs that target specific genetic disorders.