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Astros look to keep home win streak going, host Mariners

Altuve’s 2 homers and Peña’s milestone triple propel Astros past Mariners 9-2

Jose Altuve homered twice and had a season-high four RBIs and Jeremy Peña tripled for his 500th career hit to help the Houston Astros to a 9-2 win over the Seattle Mariners.

Houston Chronicle on MSN · 9h

Jose Altuve's two homers help Houston Astros get important win over Seattle Mariners

Jose Altuve had the 12th multi-homer game of his career to spark Houston over Seattle in a match atop AL West.

Fox Sports · 4h

Astros look to keep home win streak going, host the Mariners

Astros: Ryan Gusto (3-2, 4.65 ERA, 1.52 WHIP, 32 strikeouts) BETMGM SPORTSBOOK LINE: Astros -125, Mariners +106; over/under is 8 1/2 runs BOTTOM LINE: The Houston Astros will try to keep their three-game home win streak alive when they play the Seattle Mariners.

Mariners vs Astros Picks, Odds and Prediction

NBC Sports on MSN · 23h

Mariners at Astros Prediction: Odds, expert picks, starting pitchers, betting trends and stats for May 22

George Kirby is slated to take the mound for Seattle against Lance McCullers for Houston.The Astros are hoping to bounce back from an 8-4 loss and a dropped series against the Tampa Bay Rays when McCullers takes the mound today.

FOX Sports · 18h

Mariners vs. Astros Prediction, Odds, Picks - May 22

Preview the May 22 matchup between the Seattle Mariners and Houston Astros with odds over/under, game spread, betting lines and more.

The Indianapolis Star · 17h

Seattle Mariners at Houston Astros odds, picks and predictions

The Mariners picked up a 6-5 win Wednesday on the road against the Chicago White Sox, securing a series win with a second victory. The M's cashed as a moderate (-145) favorite as the Over (8.5) connected.

Mariners lose George Kirby’s debut

The Associated Press- Sports on … · 5h

George Kirby returns to the mound but struggles in Mariners' loss to Astros

Seattle's George Kirby didn't get the results he wanted in his season debut against the Houston Astros but was still encouraged in his return to the mound after a lengthy absence.

The Seattle Times · 9h

Mariners lose George Kirby’s debut; Julio Rodríguez scratched vs. Astros

George Kirby’s return to the mound ended in a loss and Julio Rodríguez was scratched from the lineup as the Mariners were thumped by the Astros.

Reuters · 19h

Mariners reinstate RHP George Kirby from injured list

The Seattle Mariners reinstated right-hander George Kirby from the 15-day injured list ahead of his start on Thursday against the host Houston Astros.

Astros, Mariners

Associated Press News · 14h

Mariners vs. Astros Starting Pitcher Matchup - May 22

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ESPN · 1d

Mariners vs. Astros (May 22, 2025) Pregame - ESPN

Pregame analysis and predictions of the Seattle Mariners vs. Houston Astros MLB game to be played on May 22, 2025 on ESPN.

Yahoo! Sports · 8h

Mariners vs. Astros Highlights

Jose Altuve and the Astros defeat Dylan Moore and the Mariners, 9-2

9hon MSN

Mariners Make Unfortunate Julio Rodriguez Announcement Before Astros Game

Mariners Make Unfortunate Julio Rodriguez Announcement Before Astros Game first appeared on Athlon Sports on May 22, 2025 ...

Yardbarker on MSN2h

Mariners await positive pitching news amid series in Houston

The series opener against the host Houston Astros on Thursday resulted in a loss for the Mariners as a team, but the Seattle ...

12hon MSN

Mariners' Julio Rodriguez late scratch in opener vs. Astros

Mariners center fielder Julio Rodriguez was scratched about 30 minutes before Thursday's series opener against the Astros.

19h

Showdown: Mariners at Astros Series Preview

The Astros have sort of limped along in the muddy middle of the American League standings. As recently as May 14, they were a ...

23h

How to Watch Mariners vs. Astros: TV Channel & Live Stream - May 22

Preview the May 22 matchup between the Seattle Mariners and Houston Astros with recent trends, how to watch, livestream info, ...

1don MSN

Seattle Mariners' Rival Dealing with Another Injury Issue Before Huge Weekend Series

The Seattle Mariners are about to finish up their 10-game road trip with four games in Houston against the Astros, and ...

Astros' Ronel Blanco: Getting sore elbow examined

Blanco has been sent back to Houston to be evaluated after reporting right elbow soreness Monday, Matt Kawahara of the Houston Chronicle reports. Blanco had been scheduled to start this weekend ...

Mariners’ bats go cold in loss to White Sox on chilly night in Chicago

After a lengthy rain delay to start the game, the Mariners are held to just four hits and fall to the White Sox 1-0 on a ...

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