ZME Science on MSN

Doctors Are Now Using Car-T Cell Therapy to Treat Autoimmune Diseases

CAR-T stands for Chimeric Antigen Receptor T-cell therapy. Doctors harvest the patient’s T cells, the soldiers of the immune ...

Sequencing method can analyze millions of T cells at a fraction of the cost

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant ...
Fred Hutchinson Cancer Center

For many blood cancer patients, CAR T-cell therapy is game-changing

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has been extremely effective ...
EMBO Press

Murine T-cell receptor OT-I exhibits imperfect discrimination between foreign and self-antigens

The OT-I mouse T-cell receptor (TCR) is thought to perfectly discriminate between lower-affinity self- and higher-affinity ...
CURE

LYMPHIR Launches in U.S., Bringing New Option for Stage 1 to 3 CTCL

The U.S. commercial launch of LYMPHIR (denileukin diftitox-cxdl), a novel cancer immunotherapy for adults with relapsed or ...
EMBO Press

Dynamics of checkpoint receptors in γδ T cell subsets are associated with clinical response during anti-PD-1 immunotherapies

Different subsets of γδ T cells display differential expression of immune checkpoint receptors (ICRs) and have distinct ...

Lyell Immunopharma Presents New Clinical Data from Ongoing Trial of Ronde-Cel Showing High Rates of Durable Complete Responses in Patients with Large B-cell Lymphoma at the ...

B-cell lymphoma in the 3L+ setting 83% overall response and 61% complete response rates in cohort comprised predominantly of patients with primary refractory large B-cell lymphoma in the 2L setting ...
GEN

Computationally Designed Receptors Help Engineered T Cells Control Tumors

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
ascopubs.org

Chimeric Antigen Receptor-T Cells in Colorectal Cancer: Pioneering New Avenues in Solid Tumor Immunotherapy

Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...