Subcellular localisation of RNA transcripts is a fundamental mechanism of post-transcriptional gene regulation, enabling neurons to respond locally to activity-dependent stimuli in dendrites, axons, ...
Kinetoplastids are single-celled, flagellated eukaryotes that include important parasites of humans, livestock and crop plant species and are typically transmitted by invertebrates. Within this class ...
The spatial and temporal distributions of proteins are critical to protein function, but cannot be directly assessed by measuring protein bundance. Here we describe a mass spectrometry-based ...
Although numerous spatial transcriptomics analyses exist for evaluating RNA localization, these methods face several limitations. Cell fractionation techniques, such as density gradient centrifugation ...