The capacity of wild-type p53 (wtp53) to bind certain DNA structures plays a crucial role in the execution and coordination of its tumor suppressor activities. Sequence-dependent interactions mediate ...

As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub. Its main purpose is to provide the ...

Background. Kaposi sarcoma-associated herpesvirus (KSHV) establishes lifelong infection in the human host and has been associated with a variety of malignancies. KSHV displays striking geographic ...

November 4, 2010 – The autoimmune disease type 1 diabetes (T1D), also known as juvenile diabetes, is diagnosed in approximately 70,000 children worldwide per year. Genetics is increasingly being ...

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to ...

In September 1970, Janet Mertz joined the biochemistry department at Stanford University. She was one of only six new graduate students in the department and the first female one admitted in nine ...

New studies underscore how coronaviruses frequently mix their genetic components — which could contribute to the rise of dangerous variants. By Roxanne Khamsi In recent weeks, scientists have sounded ...

When the genomes of parents come together to create the genome of a child, their DNA recombines; similar parts are rearranged so that a child carries sections of their parents genomes that have been ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) are members of the subgenus Sarbecovirus, whose genomic length is around ...

PALO ALTO, Calif.--(BUSINESS WIRE)--In a leap forward for genetic engineering, a team of researchers from the Arc Institute has discovered the bridge recombinase mechanism, a precise and powerful tool ...