Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...
New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...
Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell–cell contacts and are also considered likely to be tumor suppressors but how they function is ...
Morning Overview on MSN
Scientists watch drug molecules hit cell receptors in real time
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...
Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...
A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) ...
Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...
Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
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