The quality and safety of a biopharmaceutical is determined by how well its manufacture is controlled. The challenge is that the modeling methods used to develop control strategies sometimes struggle ...

Rated as one of the top ten journals in healthcare administration, Medical Care is devoted to all aspects of the administration and delivery of healthcare. This scholarly journal publishes original, ...

A behind-the-scenes blog about research methods at Pew Research Center. For our latest findings, visit pewresearch.org. Identifying causal relationships from observational data is not easy. Still, ...

This is a preview. Log in through your library . Abstract Applied sciences, including longitudinal and clustered studies in biomedicine, require analyses of ultrahigh-dimensional linear mixed-effects ...

Mixed-effects location scale models represent a powerful statistical framework designed to investigate longitudinal data. By simultaneously modelling the mean trajectories (location) and residual ...