Post-translational modifications are an area of great interest in mass spectrometry-based proteomics, with a surge in methods to detect them in recent years. However, post-translational modifications ...
In proteomics applications of tandem mass spectrometry (MS/MS), one of the core analysis challenges is the de novo sequencing problem: given an observed fragmentation spectrum, can we infer the amino ...
Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...