Nuclear receptors are popular targets for drug companies searching for new therapeutics for cancer and cardiovascular, metabolic, inflammatory, and other diseases. Indigo Biosciences in State College, ...

Nuclear receptors are receptors that bind to a ligand that has crossed the cell membrane, after which the ligand-bound receptor binds to DNA to regulate gene expression. These receptors are key ...

Image Caption: Epigenetic regulation of receptors. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of ...

Researchers have found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD). While researchers have ...