Neural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives ...

Tsukuba, Japan - Placodes and neural crests are defining features of vertebrates (animals with a spinal cord surrounded by cartilage or bone). Placodes are embryonic structures that develop into ...

This is a preview. Log in through your library . Abstract Wnt signaling has recently emerged as a key factor in controlling stem cell expansion. In contrast, we show here that Wnt/β-catenin signal ...

The neural crest is a transient embryonic tissue that gives rise to a multitude of derivatives in an axially restricted manner. An in vitro counterpart to neural crest can be derived from human ...

Transplantation of cells from the sympathoadrenal lineage has been suggested in the treatment of neurodegenerative diseases and pain. Currently, this approach is not practical due to a shortage of ...

Researchers have elucidated the evolutionary origins of placodes and neural crests, which are defining features of vertebrates, through lineage tracing and genetic analysis in Ciona intestinalis, a ...