A new study upends movement disorder research, proving Purkinje cells are a poor biomarker for deep cerebellar nuclei.

The ability to sequence entire exomes and genomes has revolutionized molecular testing in rare movement disorders, and genomic sequencing is becoming an integral part of routine diagnostic workflows ...

Scientists have uncovered a surprising new genetic cause of a rare movement disorder after analyzing nearly 3,000 patients ...

Huntington disease is a rare, inherited brain disorder that progressively destroys nerve cells, leading to worsening movement ...

Cholinergic system degeneration is a hallmark of Lewy body disease, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), but its involvement in prodromal stages, particularly ...

Researchers use zebrafish models to discover that the RLS risk gene MEIS1 regulates Purkinje cell survival and motor control.

A research team has published a randomized clinical trial demonstrating for the first time that a multidisciplinary approach integrating specific physiotherapy and cognitive-behavioral therapy is ...

Researchers identified the immune cGAS-STING pathway as a key contributor to harmful inflammation. Using a humanized mouse model of Huntington disease, they found that blocking this pathway – either ...

Tardive dyskinesia (TD) is an involuntary movement disorder caused by long-term dopamine-blocking medications. Prolonged use may create chemical imbalances in brain areas controlling movement.

Early diagnosis improves cancer outcomes by providing care at the earliest possible stage and may increase the chance of survival compared to when it is detected at a later stage. Now, a new study in ...

Stereotypic movement disorder is a motor disorder that develops in childhood, typically before grade school, and involves repetitive, purposeless movement. Examples of stereotypic movements include ...