To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

This work reviews CM-cfDNA methods applied to clinical oncology, emphasizing both machine learning (ML) techniques and mechanistic approaches. The latter integrate biological principles, enabling a ...

It's tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...

Researchers at the University of Oregon have developed an artificial intelligence tool that can read genetic code the way large language models like ChatGPT read text. Scanning the genome for ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...