The Ink4a/Arf locus encodes two tumour-suppressor proteins that are specified in part by the unprecedented use of alternative reading frames within a common second exon of both genes 1. The first ...
Researchers have broken new ground in the understanding of the MDM2 gene -- which is often overexpressed in cancer -- finding that when it acts with a specific protein, it can lead to cancer cell ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 3 (Jan. 18, 2005), pp. 731-736 (6 pages) The MYCN oncogene is the major negative prognostic marker in ...
Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene--which is often overexpressed in cancer--finding that when it acts with a specific protein, it can lead to cancer ...
While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the globe, it fails in a significant ...
(New York, NY - May 2, 2019) -- Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene--which is often overexpressed in cancer--finding that when it acts with a specific ...
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