Understand why routine lactate rechecks every 3–4 hours for days, prompting more fluids and vasopressors, can worsen outcomes ...
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...
AARS, Alanyl-tRNA synthetase; AKT, protein kinase B; CC, cervical cancer; DCBLD1, discoidin, CUB, and LCCL domain-containing protein 1; EC, endometrial cancer; G6PD ...
The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more respiratory infections. International research led by the Radboudumc shows how this ...
The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
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