c-Jun N-terminal protein kinases (JNK), also known as stress-activated protein kinases, were originally identified by their ability to phosphorylate the N-terminal of the transcription factor c-Jun ...

The C-Jun N-Terminal Kinase (JNK) signalling pathway plays a pivotal role in regulating cellular responses to stress and damage. As a member of the mitogen-activated protein kinase (MAPK) family, JNK ...

Loss of A20 function in hepatic stellate cells upregulated the DCLK1-JNK phosphorylation axis. DCLK1 enhances chemokine expression, leading to progression of chronic hepatitis. Researchers from Tokyo ...

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade ...