A case report highlights pulmonary siderosis in a welder with progressive dyspnea and recurrent infections, underscoring occupational history, possible systemic iron overload, and the need to monitor ...

Expert Rev Mol Diagn. 2010;10(6):755-763. The diagnosis is based on a three-step strategy. The first step is recognizing clinical signs and symptoms. Many symptoms in various combinations may suggest ...

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia. Patients with ...

DANVILLE, Pa. – Genomic screening to identify hemochromatosis—a disorder that causes iron levels in the body to rise to dangerous levels—encourages people with the condition to seek treatment and ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload.

Hemochromatosis is a condition in which too much iron builds up in the body. When people inherit the condition via their genes, it can be heterozygous or homozygous. “Heterozygous” means the person ...

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...

When you’re pregnant, you hear a lot about iron deficiency. Doctors, books, and articles all stress how important it is to get enough iron for you and your baby. But what if the problem isn’t too ...