DNA gyrase, a bacterial type II topoisomerase, is instrumental in maintaining DNA supercoiling during replication and transcription. Owing to its absence in higher eukaryotes, it represents an ...
These two images demonstrate synthetic lethality with a non-responsive cell line (right) compared to a responder to ATR ...
A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center ...
Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified ...
Funding to support Phase 1 clinical development of best-in-class PARG inhibitor candidate FORX-428FORX-428 is potential new treatment option for ...
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Researchers identify Rb1 as a predictive biomarker for a new therapeutic strategy in some breast cancers
A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive ...
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