Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary ...

Scientists from Toronto's Princess Margaret Hospital are able to depict for the first time how an important molecule called IP3 and its receptor interact to control calcium levels in cells, a process ...

Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...

Dying cells are typically expelled from epithelial sheets to prevent foreign substances and microorganisms from entering, but the mechanism underlying this process is unclear. A recent study has ...