Antibody humanization involves modifying antibodies from non-human sources, such as mice, to decrease their immunogenicity in human applications. While mouse monoclonal antibodies are specific, they ...
The global antibody discovery market, valued at USD 11.15 billion in 2025, is expected to surge to USD 35.35 billion by 2035, ...
Antibodies are a critical feature of the human adaptive immune response. New immunotherapies require the production of selective and non-autoimmunogenic antibodies. These engineered antibodies can ...
Understanding human gene function in living organisms has long been hampered by fundamental differences between species.
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A recent study explored the therapeutic potential of hu128.1, a humanized antibody targeting transferrin receptor 1 (TfR1), in treating erythroleukemia using xenograft mouse models. The results ...
-- Blocking of α5β1 integrin has been shown to improve motor function and increase survival in the SOD1 G93A mouse model of ALS -- -- Fully humanized anti-α5β1 monoclonal antibody is ready for ...
Additional Prognostic Value of Bone Marrow Histology in Patients Subclassified According to the International Prognostic Scoring System for Myelodysplastic Syndromes Purpose: To evaluate the ...
Researchers have identified a promising new weapon against triple-negative breast cancer, one of the most aggressive forms of ...