Fluorine has changed the world of medicine. You might not see it, but newly approved drugs contain at least one fluorine atom. This tiny but powerful element is the "hidden engine" that makes our ...

Active drug agents have been chemically modified with fluorine for decades, owing to its numerous therapeutic effects: Fluorine can strengthen the bonding of the active agent to the target molecule, ...

Fluorination of therapeutic agents is a widely used strategy in the pharmaceutical industry. It improves a drug’s molecular properties, such as drug-target interactions, bioavailability, and ...

A German-US coalition of researchers from Goethe University Frankfurt (Germany) and the University of Michigan (MI, USA) have added a new element to the production of an antibiotic, erythromycin, to ...

The use of the element fluorine to modify active substances is an important tool in modern drug development. A team at Goethe University Frankfurt has now achieved an important “first” by successfully ...

A novel chemoenzymatic method can add fluorine atoms to natural compounds. The method uses an enzyme that acts as a gatekeeper for precursors and designs a pinch of precursor tolerance to create a ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...