The extracellular matrix (ECM) is a dynamic structure that is constantly remodelled to control tissue homeostasis. The ECM in mammals is composed of around 300 proteins, known as the core matrisome.

Scientists have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Scientists at the University of Helsinki have ...

In most tissues, cells are surrounded by an extracellular matrix (ECM) containing proteins such as collagen, laminin, and fibronectin. The ECM plays an important role in regulating cell function. ECM ...

Future Oncol. 2012;8(11):1427-1442. In the following sections we discuss the different constituents of the microenvironment and how they are influenced and modified by the tumor cells. Taken together, ...

A joint research team develops robust and stretchable extracellular matrix (ECM) membrane reinforced by nanofiber scaffolds. Animal models are widely used for evaluating a drug in its development ...