L-type Ca²⁺ currents determine the shape of cardiac action potentials (AP) and the magnitude of the myoplasmic Ca²⁺ signal, which regulates the contraction force. The auxiliary Ca²⁺ channel subunits ...
The ability to modify the intracellular concentrations of divalent calcium ions is vital to normal cell functioning. In the cells of the cardiac muscle, calcium ions play a crucial role in coupling ...
The ryanodine receptors (RyRs) are intracellular calcium channels responsible for rapid release of Ca 2+ from the sarcoplasmic/endoplasmic reticulum (SR/ER) to the ...
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