Scientists have long known that human genes spring into action through instructions delivered by the precise order of our DNA, directed by the four different types of individual links, or "bases," ...
Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.
The University of California San Diego researchers used artificial intelligence to identify a DNA activation code, which was previously known to be "an enigma," but can later be utilized in n ...
Why don't trees ever get sunburned? And could we harness their secret to protect our own skin? Researchers are studying how proteins called photolyases, which have been lost to humans through ...
You have full access to this article via your institution. Therefore, we tested whether generation of ROS by UVB is involved in UVB-induced apoptosis and may represent the additional pathway involved.
TFAM (transcription factor A, mitochondrial) is a DNA-binding protein that activates transcription at the two major promoters of mitochondrial DNA (mtDNA)—the light strand promoter (LSP) and the heavy ...
CD20-immunotargeting of malignant melanoma. Background: Inability to repair ultraviolet light (UV)-induced DNA damage causes skin cancer. Chloroquine has been shown to activate the DNA damage response ...
What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers ...
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