DSBs arise from genotoxic insults and normal physiological processes such as DNA replication 1. The ATM protein, a member of the PI3K-like kinase family, is mutated in patients with ataxia ...
Ultraviolet (UV) light is a potent mutagenic and genotoxic agent. Whereas DNA damage induced by UV light is known to be responsible for UV-induced genotoxicity, its role in triggering apoptosis is ...
Scientists have long known that human genes spring into action through instructions delivered by the precise order of our DNA, directed by the four different types of individual links, or “bases,” ...