The binding of T cell antigen receptors (TCRs) to specific complexes of peptide and major histocompatibility complex (pMHC) is typically of very low affinity, which necessitates the use of multimeric ...
The ligation of T cell antigen receptors (TCRs) activates the receptor-associated tyrosine kinase Lck, which then phosphorylates and modulates the functions of its protein substrates, including the ...
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