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Array-based comparative genomic hybridization (CGH) is a technique that allows genome wide screening of gains and losses in DNA copy number.
When microarray-based comparative genomic hybridisation (array-CGH) became available, all HR-CGH-positive samples were also investigated by 1 Mb resolution array-CGH for more precise mapping.
A single catalog array design, Human CGH 12x135K Whole-Genome Tiling v2.0, is available and enables genome-wide detection of copy number gains and losses down to ~100kb in size.
The use of array-based technologies (array CGH and SNP arrays) can identify deletions and amplifications in a subset of MDS and AML patients that probably contain genes that contribute to ...
Array-based comparative genomic hybridization is able to unveil previously undetectable nuances.
They recommended that advanced genomic technologies, such as array CGH, be broadly deployed by cell culture banks to ensure consistency of the cells they provide to the research community.
Methods: We performed genome-wide single nucleotide polymorphism (SNP) and copy number variant (CNV) analysis of tumor DNA obtained from 22 patients with GIST using high density arrays (HAD) ...
Detection of CNAs in AML As with MDS, early studies in AML with array CGH and SNP array showed the feasibility of interrogating AML genomes with array platforms and demonstrated their utility in ...
NimbleGen CGH 12x135K arrays will allow simultaneous analysis of 12 independent sample pairs on a single microarray slide, each with 135,000 empirically tested long oligonucleotide probes. This new ...
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