A catalyst that effectively converts amides to amines at low temperature under low hydrogen pressure has been demonstrated by a team of researchers. Amines are vital in nature; for example, amino ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

Amide bonds connect the amino acids in proteins and occur in many other useful molecules. An amide-forming reaction that turns the conventional approach on its head offers a practical way of making ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...

Chemists have been using the Schmidt reaction, which transforms aldehydes and ketones into amides, for nearly 100 years. But the reaction has a downside that prevents it from being widely used: it ...

Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing. It is well known that amide-formation chemistry can be inefficient and warrants further ...

Historically, one of the primary ways organic chemists have explored and created compounds is by constructing a carbon skeleton and making modifications to its structure. But instead of building a ...

Polymers are one of the most important elements of modern-day society, particularly in the form of plastics. Unfortunately most common polymers are derived from fossil resources, which not only makes ...