The current guideline-recommended creatinine-based eGFR equation incorporates a race coefficient that may overestimate eGFR in Black adults and contribute to discordant care. Among equations for ...

A team of mathematicians and pharmaceutical scientists collaborated to identify the major cause of the low accuracy of the equation in the FDA guidance used to predict drug-drug interaction through an ...

A systematic review found that alternative approaches to calculating estimated glomerular filtration rate (eGFR) were worth looking into to properly account for diversity in populations. A review ...

Current equations for estimated glomerular filtration rate (eGFR) that use serum creatinine or cystatin C incorporate age, sex, and race to estimate measured GFR. However, race in eGFR equations is a ...

Drugs absorbed into the body are metabolized and thus removed by enzymes from several organs like the liver. The how fast the drug is cleared out of the system can be increased by other drugs that ...