Ohtani made his first major league pitching appearance in almost two years Monday night, and the stakes are high for the defending World Series champions.

Shohei Ohtani could return to a major league mound in the next two weeks but Los Angeles Dodgers rookie right-hander Roki Sasaki has paused his throwing program and is set for a lengthy layoff.

Oddsmakers have implied with the moneyline set for this matchup that the Padres have a 35.7% chance of pulling out a win.