After drafting Georgia edge rusher Mykel Williams in the first round, the San Francisco 49ers doubled down on rebuilding their defensive front by selecting Texas Longhorns defensive tackle Alfred Collins with the 43rd overall pick in the second round of the 2025 NFL Draft.

Another Texas football player came off the board in the second round of the NFL draft on Friday. Alfred Collins, an athletic defensive lineman for the Longhorns, was picked No. 43 overall to the San Francisco 49ers.

Defensive tackle Alfred Collins was selected by the San Francisco 49ers with the 43rd overall pick in the NFL draft. Collins put it all together for the Longhorns in 2024, blossoming into a second-team All-American and first-team All-SEC defensive lineman in his fifth season in Austin. He was honorable mention All-Big 12 in 2023.